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Screen by Glaxo Group Research of eukarytic microbial strains for the bioreduction of ( rac )-bicyclo[3.2.0]hept-2-en-6-one. Adapted with permission from [ <xref ref-type= 89 ]. 1983. Royal Society of Chemistry." width="250" height="auto" />
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Screen by Glaxo Group Research of eukarytic microbial strains for the bioreduction of ( rac )-bicyclo[3.2.0]hept-2-en-6-one. Adapted with permission from [ <xref ref-type= 89 ]. 1983. Royal Society of Chemistry." width="100%" height="100%">

Journal: Molecules

Article Title: Bicyclo[3.2.0]carbocyclic Molecules and Redox Biotransformations: The Evolution of Closed-Loop Artificial Linear Biocatalytic Cascades and Related Redox-Neutral Systems

doi: 10.3390/molecules28217249

Figure Lengend Snippet: Screen by Glaxo Group Research of eukarytic microbial strains for the bioreduction of ( rac )-bicyclo[3.2.0]hept-2-en-6-one. Adapted with permission from [ 89 ]. 1983. Royal Society of Chemistry.

Article Snippet: Interesting in this respect is that while S. cerevisiae RM9, like the commercial bakers’ yeast strain studied previously by Glaxo Group Research, bioreduced the unsubstituted ( rac )-bicyclic ketone to principally the (+)-( 1S , 5R , 6S )- endo -alcohol, two of the other tested yeast strains (RM1 and ML31) produced the corresponding (-)-( 1R , 5S , 6R ) enantiomer as the principal bioreduction product.

Techniques:

Bioreduction of substituted ( rac )-bicyclo[3.2.0]heptenones by a washed cell suspension of Saccharomyces cerevisiae compared to the biooxidation of equivalent heptenols by a washed cell suspension of Bacillus stearothermophilus . Adapted with permission from [ <xref ref-type= 124 ]. 1994. Elsevier." width="100%" height="100%">

Journal: Molecules

Article Title: Bicyclo[3.2.0]carbocyclic Molecules and Redox Biotransformations: The Evolution of Closed-Loop Artificial Linear Biocatalytic Cascades and Related Redox-Neutral Systems

doi: 10.3390/molecules28217249

Figure Lengend Snippet: Bioreduction of substituted ( rac )-bicyclo[3.2.0]heptenones by a washed cell suspension of Saccharomyces cerevisiae compared to the biooxidation of equivalent heptenols by a washed cell suspension of Bacillus stearothermophilus . Adapted with permission from [ 124 ]. 1994. Elsevier.

Article Snippet: Interesting in this respect is that while S. cerevisiae RM9, like the commercial bakers’ yeast strain studied previously by Glaxo Group Research, bioreduced the unsubstituted ( rac )-bicyclic ketone to principally the (+)-( 1S , 5R , 6S )- endo -alcohol, two of the other tested yeast strains (RM1 and ML31) produced the corresponding (-)-( 1R , 5S , 6R ) enantiomer as the principal bioreduction product.

Techniques: Suspension

Bioreduction by growing cultures of various yeasts and fungi of ( rac )-bicyclo[3.2.0]hept-2-en-6-one (ketone 1), ( rac )-4-methylbicyclo[3.2.0]hept-2-en-6-one (ketone 2), ( rac )-1-methylbicyclo[3.2.0]hept-2-en-6-one (ketone 3), and ( rac )-1,4-dimethylbicyclo[3.2.0]hept-2-en-6-one (ketone 4). Adapted with permission from [ <xref ref-type= 127 ]. 1996. Elsevier." width="100%" height="100%">

Journal: Molecules

Article Title: Bicyclo[3.2.0]carbocyclic Molecules and Redox Biotransformations: The Evolution of Closed-Loop Artificial Linear Biocatalytic Cascades and Related Redox-Neutral Systems

doi: 10.3390/molecules28217249

Figure Lengend Snippet: Bioreduction by growing cultures of various yeasts and fungi of ( rac )-bicyclo[3.2.0]hept-2-en-6-one (ketone 1), ( rac )-4-methylbicyclo[3.2.0]hept-2-en-6-one (ketone 2), ( rac )-1-methylbicyclo[3.2.0]hept-2-en-6-one (ketone 3), and ( rac )-1,4-dimethylbicyclo[3.2.0]hept-2-en-6-one (ketone 4). Adapted with permission from [ 127 ]. 1996. Elsevier.

Article Snippet: Interesting in this respect is that while S. cerevisiae RM9, like the commercial bakers’ yeast strain studied previously by Glaxo Group Research, bioreduced the unsubstituted ( rac )-bicyclic ketone to principally the (+)-( 1S , 5R , 6S )- endo -alcohol, two of the other tested yeast strains (RM1 and ML31) produced the corresponding (-)-( 1R , 5S , 6R ) enantiomer as the principal bioreduction product.

Techniques: